1) Although rabbits generally will not eat or drink while in a moving vehicle, it is wise to provide them with water or a moist carrot.
2) To relieve stress, play a popular radio station in the rabbitry periodically. Then tune to the station while travelling and the rabbits will hear something familiar.
3) Make sure carriers are not crammed together in a manner that will allow rabbits to fight or bite at each other through the wire.
4) Use bungie cords to secure the carriers in the back of the moving vehicle, otherwise fast stop and starts will send them flying.
5) Never leave rabbits in an enclosed car when the weather is warm or even slightly warm. A number of studies have shown that the temperature in an enclosed car or truck can be more than 30 degrees above the outside temperature after less than 20 minutes, and more than 40 degrees within a half-hour.
7) Protect rabbits from sun by putting up sun reflective tints or shades on the car windows. Shaded windows can reduce the effects of the sun by as much as 80%.
8) Place carrier on an foam pad (the egg crate type of mattress pads work well). This will minimize the rough ride and make it easier on the rabbits. Hay in the carriers also helps to pad the ride. However if travelling from the US through Canada, hay should not be used at all.